Director
Andrew Saykin, Psy.D., ABCN
Raymond C. Beeler Professor of Radiology Director,
IU Center for Neuroimaging
Department of Radiology,
Indiana University School of Medicine
Raymond C. Beeler Professor of Radiology Director,
IU Center for Neuroimaging
Department of Radiology,
Indiana University School of Medicine
Dr. Saykin joined the Indiana University School of Medicine faculty in November 2006 as director of a new transdisciplinary center of excellence in neuroimaging. The goals of the center are: 1) to utilize imaging technologies to advance the understanding of brain function and anatomy in healthy and clinical populations and though translational studies of animal models; 2) to investigate the relationship between genetic variation and phenotypic expression structurally and functionally in health, illness, and following treatment; 3) to provide training and experience in advanced brain imaging research methods; and 4) to develop, assess, and validate emerging technologies that optimize the use of molecular and functional imaging methodologies including PET, fMRI, DTI, MRS, perfusion and morphometry as well as image analysis strategies and bioinformatics.
Dr. Saykin's own NIH and foundation sponsored research program focuses on the use of brain imaging and genomic methods to study mechanisms of memory dysfunction and treatment response in neurological and psychiatric disorders. Current projects examine advanced imaging methods for early preclinical detection of Alzheimer's disease (NIA R01 AG19771), the neural basis of cancer chemotherapy-induced cognitive changes (NCI R01 CA101318), and alterations in brain activity and connectivity in schizophrenia (U54 EB005149). Each project includes a component examining genomic correlates of brain imaging phenotypic markers.
Education/Training
Graduate: Hahnemann Medical College, Philadelphia, PA
Post-Doctoral Fellowship: University of Pennsylvania, Philadelphia, PA
Selected Publications
1. Saykin AJ, Shen L, Risacher SL, Kim S, Nho K, West JD, Forond TM, and the ADNI. Genetic
predictors of 12 month change in MRI hippocampal volume in the Alzheimer’s Disease
Neuroimaging Initiative cohort: Analysis of leading candidates from the AlzGene database. Int.
Conf. on Alzheimer's Disease (ICAD), selected for oral presentation, July 11-16, 2009, Vienna,
Austria.
2. McDonald BC, Saykin AJ, West JD, Sullivan JE, Detre JA. (2009). Medial Temporal Lobe fMRI
Activation During Episodic Memory Processing in Children. International Neuropsychological
Society Annual Meeting. Atlanta, GA.
predictors of 12 month change in MRI hippocampal volume in the Alzheimer’s Disease
Neuroimaging Initiative cohort: Analysis of leading candidates from the AlzGene database. Int.
Conf. on Alzheimer's Disease (ICAD), selected for oral presentation, July 11-16, 2009, Vienna,
Austria.
2. McDonald BC, Saykin AJ, West JD, Sullivan JE, Detre JA. (2009). Medial Temporal Lobe fMRI
Activation During Episodic Memory Processing in Children. International Neuropsychological
Society Annual Meeting. Atlanta, GA.
3. Ramanan VK, Risacher SL, Nho K, Kim S, Swaminathan S, Shen L, Foroud
TM, Hakonarson H, Huentelman MJ, Aisen PS, Petersen RC, Green R C, Jack
CR, Koepp, RA, Jagust W J, Weiner M W, Saykin AJ (2013) APOE and BCHE
as modulators of cerebral amyloid deposition: a florbetapir PET genome
wide association study. Molecular Psychiatry. Published online, Feb. 9,
2013. doi:0.1038/mp.2013.19.
TM, Hakonarson H, Huentelman MJ, Aisen PS, Petersen RC, Green R C, Jack
CR, Koepp, RA, Jagust W J, Weiner M W, Saykin AJ (2013) APOE and BCHE
as modulators of cerebral amyloid deposition: a florbetapir PET genome
wide association study. Molecular Psychiatry. Published online, Feb. 9,
2013. doi:0.1038/mp.2013.19.
Academic/Hospital/Administrative Appointments:
2006-present Raymond C. Beeler Professor of Radiology, Indiana University School of Medicine-Indianapolis.
2006-present Member, Breast Cancer Research Program, IU Simon Cancer Center, Indianapolis, IN.
2006-present Member, Stark Neurosciences Research Institute, Indiana University School of Medicine.
2007-present Professor, Department of Psychological and Brain Sciences, Indiana University- Bloomington.
2007-present Professor, Department of Neurology, Indiana University School of Medicine.
2007-present Professor of Clinical Psychology in Psychiatry, Indiana University School of Medicine.
2007-present Member and Neuroimaging Core Leader, Indiana Alzheimer Disease Center, Indianapolis, IN.
2007-present Faculty Mentor, MD/PhD Medical Scientist Training Program, Indiana University School of Medicine-Indianapolis.
2007-present Faculty Mentor, Medical Neuroscience PhD Program, Indiana BioMedical Gateway (IBMG).
2008-present Faculty Mentor, Medical and Molecular Genetics PhD Program, IN BioMedical Gateway (IBMG).
2008-present Professor, Department of Medical and Molecular Genetics, IU School of Medicine-Indianapolis.
2004-06 Director, NIH sponsored Neuroimaging Research Center: High Field Facility at DHMC.
2004-06 Co-Director, Dartmouth Advanced Imaging Center (DAIC), DHMC.
2006-present Director, IU Center for Neuroimaging, Indiana University School of Medicine-Indianapolis, IN
2006-present Associate Director, Indiana Institute of Biomedical Imaging Sciences (IIBIS).
2008-present Member, IU Neuroscience Center Leadership Council
Editorial Boards:
2006-present Editor-in-Chief of Brain Imaging and Behavior, Springer
2006-present Editorial Board, Neuropsychology Review
2011-present Editorial Board, Frontiers in Genomics
2011-present Editorial Board, Frontiers in Neurogenomics
2011-present Editorial Board, Frontiers in Toxicogenomics
2012-present Editorial Board, American Journal of Neurodegenerative Diseases
Last update: 04/26/2013
2006-present Raymond C. Beeler Professor of Radiology, Indiana University School of Medicine-Indianapolis.
2006-present Member, Breast Cancer Research Program, IU Simon Cancer Center, Indianapolis, IN.
2006-present Member, Stark Neurosciences Research Institute, Indiana University School of Medicine.
2007-present Professor, Department of Psychological and Brain Sciences, Indiana University- Bloomington.
2007-present Professor, Department of Neurology, Indiana University School of Medicine.
2007-present Professor of Clinical Psychology in Psychiatry, Indiana University School of Medicine.
2007-present Member and Neuroimaging Core Leader, Indiana Alzheimer Disease Center, Indianapolis, IN.
2007-present Faculty Mentor, MD/PhD Medical Scientist Training Program, Indiana University School of Medicine-Indianapolis.
2007-present Faculty Mentor, Medical Neuroscience PhD Program, Indiana BioMedical Gateway (IBMG).
2008-present Faculty Mentor, Medical and Molecular Genetics PhD Program, IN BioMedical Gateway (IBMG).
2008-present Professor, Department of Medical and Molecular Genetics, IU School of Medicine-Indianapolis.
2004-06 Director, NIH sponsored Neuroimaging Research Center: High Field Facility at DHMC.
2004-06 Co-Director, Dartmouth Advanced Imaging Center (DAIC), DHMC.
2006-present Director, IU Center for Neuroimaging, Indiana University School of Medicine-Indianapolis, IN
2006-present Associate Director, Indiana Institute of Biomedical Imaging Sciences (IIBIS).
2008-present Member, IU Neuroscience Center Leadership Council
Editorial Boards:
2006-present Editor-in-Chief of Brain Imaging and Behavior, Springer
2006-present Editorial Board, Neuropsychology Review
2011-present Editorial Board, Frontiers in Genomics
2011-present Editorial Board, Frontiers in Neurogenomics
2011-present Editorial Board, Frontiers in Toxicogenomics
2012-present Editorial Board, American Journal of Neurodegenerative Diseases
Last update: 04/26/2013
