News and Events
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The Indiana Alzheimer Disease Center at the Indiana University School of Medicine along with the USAgainstAlzheimer’s Network is sponsoring the production of Forget Me Not at the IRT in Indianapolis IN, on Thursday, July 16, 2015 at 1:00 pm. A Q & A panel session will be presented during the production to answer your questions about diagnosis, research and treatment for Alzheimer’s disease and related dementias. Visit the following You-Tube link for a preview - https://youtu.be/nJWvSugwsqQ. We invite you to save the date and register to attend. Tickets for the event are free. Reserve your tickets now by visiting www.AfricanAmericansAgainstAlzheimers.org/events or call 202-349-3803 for more information.
Forget Me Not is a Garrett Davis, national award winning stage play coming to Indianapolis to help raise awareness about Alzheimer’s disease (AD). This touching play about love and hope will bring real life situations to the stage. The creator’s thought provoking production will educate as well as entertain. Forget Me Not takes the audience into the life of a family facing this medical challenge and shows its impact on not just the immediate family but friends, marriage, and those in the community as well. Many have left the theater realizing there are people close to them who may have signs of AD. Thanks to a panel of experts presented during the event, they leave equipped with answers to important questions about medical and social services that are available in their communities and learn how researchers are working to find ways to prevent and more effectively treat AD-- important work that requires each of us-- especially African Americans who are more likely to develop AD than other groups--to consider participating in research projects. Research is the only way that we will be able to discover effective treatments for this difficult disease. The costs of AD to the African American community is severe and growing rapidly. African Americans are twice as likely to develop Alzheimer’s disease as non-Hispanic white Americans and AD is the 4th leading cause of death for older African Americans. Please get involved and join us for this unique opportunity.
When: Thursday, July 16, 2015 from 1 pm to 5 pm.
Where: Indiana Repertory Theatre at 140 W. Washington Street, Indianapolis, IN
Tickets: visit www.AfricanAmericansAgainstAlzheimers.org/events to get your Free tickets. Call 202-349-3803 for more information
June 17, 2015 After 20 years with the Department of Pathology & Laboratory Medicine and Medical and Molecular Genetics in the IU School of Medicine, Jill R. Murrell, PhD, Associate Professor, has accepted a position with John’s Hopkins University. As a Molecular Geneticist, She worked on many projects including the IADC and the Indianapolis Study on Health and Aging.
June 15, 2015 The Indiana Alzheimer Disease Center and the Indiana University School of Medicine welcome Dr. Liana Apostolova. A reception was held from 11:30 a.m. to 12:30 p.m. on Monday, June 15 in the Goodman Hall Second Floor Collaboration Space in Room 2305 Dr. Apostolova earned her M.D. in 1998 from The Medical University in Sofia, Bulgaria. She completed her medical internship at Ravenswood Hospital, located in Chicago, Ill., in 2000, followed by a neurology residency at the University of Iowa Hospitals and Clinics in Iowa City, Iowa, that lasted until 2003. Next, Dr. Apostolova spent two years serving a fellowship in dementia and behavioral neurology at UCLA in Los Angeles. While at UCLA, she earned a Master’s of Science in clinical research methodology, which was conferred in 2010. She joins the IU faculty from UCLA. Below, Drs. Saykin and Nudelman chat with Liana.
May 2015 Joey Annette Contreras, PhD candidate in Medical Neuroscience, doing research in the Center for Neuroimaging and the Indiana Alzheimer Disease Center (IADC), has been awarded a highly competitive Indiana Clinical and Translational Sciences Institute (CTSI) predoctoral training grant for translational research. Translational research most commonly refers to research that goes from "bench to bedside"; the process by which research in the lab translates into patient treatment. The goal of the awarded project involves identifying and characterizing the subtle changes that occur in both structural and functional connectivity in the brain during the early prodromal to clinical stages of Alzheimer’s disease (AD). Using network science and graph theory, Joey will work on detecting abnormal connectivity in the diseased brain’s connectome before and during the period when clinical symptoms begin to manifest. This will ultimately facilitate earlier diagnosis and improved prognostic prediction which are both critical for therapeutic development. Her mentors on the project are Drs. Andrew Saykin and Joaquín Goñi.
April 25, 2015 The first annual Neuroscience: Brain & Beyond Fair that was held in the Neuroscience Center. Twelve Indiana schools participated after a group of Neuroscientists had visited their schools to share what their research is about, and careers associated with Neuroscience. 20 projects were entered for the competition, with monetary prizes being awarded to the Science departments of winning schools.
1st place School class room winner was Crawfordsville – teacher – Shannon Hudson who will receive $1000 for her classroom2nd place school classroom winner was St. Thomas – teacher - Sandy Hoy who will receive $750 for her classroom3rd place school classroom winner was Clinton Prairie – teacher – Gail Fusaro who will receive $500 for her classroom
1st place project winners are:“Gender Response Differences” by Frannie Fuller from Crawfordsville Middle School
“Does an Almond a day keep bad grades away” by Elle Gebke from St. Thomas Aquinas
2nd place project winners are:“To Chew or Not to chew” by Emma Balaz and Noelle Baer from Crawfordsville Middle School
“Yum Yum” by Marchelle Blanchet from St. Thomas Aquinas
3rd place project winners are:“Reaction times comparisons between dominant and non-dominant hands” by Grace Walker from Crawfordsville Middle School.
“Are you lying” by Rebekah Lloyd and Sadie Smith from Clinton Prairie
Judges were Faculty members of the IU School of Medicine.
April 22, 2015 Kelly Nudelman, Ph.D., Department of Medical and Molecular GeneticsIU School of Medicine presented her Dissertation Seminar entitled, “Cognitive Dysfunction in Cancer: Neuroimaging and Genetic Approaches to Identify Biological Mechanisms” successfully. Many congratulations from Dr. Andrew J. Saykin and the Center for Neuroimaging Lab.
April 16, 2015 through the 18th is the Alzheimer Disease Centers' Annual Conference for the Directors and Administrators from each state. Dr. Andrew J. Saykin, the Director for the Indiana Alzheimer Disease Center, is attending as well as the Administrator for the IADC, Bradley S. Glazier. Mr. Glazier is giving a talk on ways to collaborate effectively.
March 16, 2015 Mert Rory Sabuncu, Ph.D. from Massachusetts, presented “Multivariate Methods in Neuroimaging Genetics” in the HITS building in Room 1110 at 11:00 am. Here is the official flyer: Mert_Rory_Sabuncu.pdf
March 6, 2015 The Indiana Alzheimer Disease Center will have the annual Scientific Symposium on Friday, March 6, 2015. We are welcoming Keynote Speakers: Andrew J. Saykin, PsyD; Bernice A. Pescosolido, PhD; Olaf Sporns, PhD; and talks from researchers: Joaquin Goni, PhD; Vijay Ramanan, PhD; and Li Shen, PhD. Please click on the links to download the brochure and agenda for complete details: IADC_2015_Scientific_Symposium_Brochure_FINAL.PDF
Nine Posters were displayed for attendees to peruse between speakers and during lunch break.
February 19, 2015 Visiting our Center today is Guest Lecturer Franco Pestilli, PhD from the Psychological and Brain Sciences Department of I.U. Bloomington. His talk is “Model based Neuroanatomy: Validation Statistical Inference in Living Connectomes” to be given at 1:30 in the Neuro-Research Building on 16th St. and Senate Ave.
November 12, 2014 PhD Candidate in Medical Neuroscience, Joey Contreras, presented a poster yesterday at the CTSI Symposium in the IUPUI Campus Center. Title: Mapping Neurodegeneration in the Human Connectome: A Network Science Study of Hereditary Diffuse Leukoencephalopathy with Spheroids. Authors: JA CONTRERAS, SL RISACHER, JD WEST,Y WU, Y WANG , JR MURRELL, MR FARLOW, F UNVERZAGT, B GHETTI, BR MATTHEWS, KA QUAID, O SPORNS, AJ SAYKIN, J GOÑI Contreras explained, "Our study focused on using the combination of deterministic tractography and network analysis to allow for the detection and characterization of profound cortical to cortical changes in integration and segregation associated with HDLS, a dominant autosomal neurodegenerative disease. Our preliminary findings suggest that advanced network analytic approaches show promising sensitivity to known white matter pathology and progression."
November 11, 2014 IU-led research team identifies genetic variant linked to better memory performance. Read more about it here: FASTKD2 is associated with memory and hippocampal structure in older adults V K Ramanan, K Nho, L Shen, S L Risacher, S Kim, B C McDonald, M R Farlow, T M Foroud, S Gao, H Soininen, I K?oszewska, P Mecocci, M Tsolaki, B Vellas, S Lovestone, P S Aisen, R C Petersen, C R Jack Jr, L M Shaw, J Q Trojanowski, M W Weiner, R C Green, A W Toga, P L De Jager, L Yu, D A Bennett and A J Saykin for the Alzheimers Disease Neuroimaging Initiative (ADNI) Mol Psychiatry advance online publication, November 11, 2014; doi:10.1038/mp.2014.142 Abstract
October 23, 2014 Indiana University investing $7 million for new complexity institute: http://news.iupui.edu/releases/iu/2014/10/iuni-network-science-institute.shtml Dr. Andrew Saykin is named as Co-Director along with Dr. Bernice Pescosolito and Dr. Olaf Sporns.
October 24, 2014 Visiting the Center for Neuroimaging in the Neuroscience Center are Dr. Olaf Sporns, from Indiana University Psychological and Brain Sciences, and Dr. Martijn van den Hauvel from Utrecht University Medical Center in the Netherlands. They are collaborating with Dr. Joaquín Goñi and others in The Center. They will have a Roundtable discussing computational neuroscience as it relates to studies they are working on in AD research.
October 15, 2014 Drs. Yang Wang and Brenna McDonald find altered regional cerebral blood flow after pediatric concussion using ASL
Drs. Yang Wang and Brenna McDonald and colleagues have just had accepted for publication in Developmental Neuropsychology a study that details the use of arterial spin labeling in chronic pediatric mild traumatic brain injury (mTBI; i.e. concussion).
Your child may have or will experience concussion during their childhood—a little rest and parental care is usually what the doctor ordered. However, after concussion symptoms subside, the brain is still changing.
Concussion (mTBI) pathophysiology is at best poorly understood. It is a significant public health problem, since concussion can make a child more prone to developing emotional, behavioral, and cognitive problems. In addition, concussion makes the pediatric brain more susceptible to a second injury.
“Decreased cerebral blood flow in chronic pediatric mild TBI: an MRI perfusion study” is the first study of its kind to explore cerebral blood flow changes in mTBI. This is important for the development of novel therapeutics that could alleviate symptoms and prevent repeat injury.
“This is the first research paper to evaluate cerebral blood flow changes in pediatric mild traumatic brain injury using the advanced MR perfusion technique,” states Wang.
The investigative team measured cerebral blood flow (CBF) in order to understand the neurovascular mechanisms related to concussion and recovery, and how concussion impacts brain function and susceptibility to further injury.Wang and McDonald used arterial spin labeling (ASL) to noninvasively assess cerebral blood flow in chronic pediatric mTBI patients compared to healthy controls. ASL is an advanced MRI technique that uses magnetically labeled blood water for a tracer, dodging the traditional concerns of pediatric radiation exposure.
The study consisted of 14 adolescents with mTBI, who had a concussion due to participation in recreational sports 3-12 months previously. Healthy controls consisted of 15 adolescents with no history of concussion. Normal MRI and neuropsychological tests indicated no difference between the mTBI group and healthy controls.
Lower CBF in bilateral frontotemporal brain regions was found in the mTBI patients approximately seven months post-injury. These regions are important for executive function and decision making, and are regions undergoing active maturation in adolescence. Thus, Wang and McDonald concluded, pediatric concussion may trigger a pathophysiologic process that results in altered regional CBF.
McDonald noted, “These findings are important because they demonstrate persistent brain alterations well after the typical period of symptom recovery, which may help explain vulnerability to subsequent injury.” Exploring this process and the mechanism behind it may be useful in future development of novel therapeutics for concussion.
Complete list of authors:
Yang Wang, MD 1,2*, John D. West, MS 2, Jessica N. Bailey, BS 2, Daniel R. Westfall, BA 2,3, Hui Xiao, MD 2,4, Todd W. Arnold, MD 5, Patrick A. Kersey, MD 5, Andrew J. Saykin, PsyD 2, Brenna C. McDonald, PsyD 2*1 Center for Imaging Research, Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA; 2 Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; 3 Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA 4 Department of Radiology, Dongfang Hospital, Fujian, China; 5 St.Vincent Sports Performance, Carmel, IN, USA
October 6, 2014 Neuroscientists receive Nobel Prize for finding Spatial Navigation cells in the brain: http://www.nobelprize.org/nobel_prizes/medicine/laureates/2014/press.pdf
Friday, October 3, 2014 IUPUI Imaging Research Symposium IUPUI University Library, Lilly Auditorium10:00am – 3:00pm The objective of this Symposium was to bring together investigators from diverse scientific disciplines with image technology experts to explore potential collaborative research opportunities. This year’s event included a presentation by Dr. Kamlesh Lulla, Chief Scientist for Earth Observations from NASA’s Johnson Space Center who will describe recent activities in remote imaging. In addition, several IUPUI investigators presented their imaging-related research activities. These include applications in neuroimaging in Alzheimer’s disease, 3D imaging of the human airway, live cell imaging, and molecular probe development for tumor imaging among other topics. A poster session will provided opportunity for attendees to interact with several investigators who develop or utilize imaging technologies in their research. The target audience included researchers within the IUPUI/IU/PU community as well as academic and industrial investigators within the greater Indiana research community.
For more information, visit http://www.imaging.iupui.edu/events.php
September, 2014 Dr. Andrew J. Saykin was recently interviewed by Mike Jansen, Praxis Media Group, for a PBS series about storytelling. Dr. Saykin talked about how the brain processes information as it relates to learning.
August 28, 2014 Dr. Yang Wang will be missed as he joins the Medical School in the University of Wisconsin. Yang was with the I.U.S.M. for 15 years, making great contributions to the research here.
August 26, 2014 The Alzheimer's Association has chosen Shannon L. Risacher, Ph.D., as one of the 2014 New Investigator Research Grant recipient. NIRG Funds the next generation of promising scientists who have earned their doctoral degrees within the last 10 years. New Investigator Research Grants help to Promote Diversity (NIRGD) Funds new investigators from diverse backgrounds with intent to support early career development that will lay groundwork for future research grants.
August 19, 2014 Indiana University School of Medicine has purchased Siemens' most State-of-the-Art PRISMA 3T MRI scanner for patient care and research. It was installed in the Neuroscience Center by a crane large enough to hold this 30 ton machine. See more details here:
August 14, 2014 Ruth Lilly Medical Library Room 317. Candidate Talk: Chair, Medical and Molecular Genetics, Dr. Jason Moore, Third Century Professor; Professor, Genetics and Community and Family Medicine; Director, Institute for Quantitative Biomedical Sciences Geisel School of Medicine, Dartmouth College speaking on: “Network science approaches to the genetic analysis of common human diseases”.
Dr. Moore’s NIH-funded research program focuses on the development, evaluation and application of computational methods for identifying and characterizing gene-gene and gene-environment interactions in population-based studies of common human diseases. His work has been communicated in more than 380 publications and is supported by several NIH R01 grants including three from the National Library of Medicine. In 2011 he was elected a Fellow of the American Association for the Advancement of Science (AAAS) in recognition of his scholarship in the area of computational human genetics. He was selected as a Kavli Fellow of the National Academy of Sciences in 2013 and serves as founding Editor-in-Chief of the BioMed Central journal BioData Mining.
NSRI (Neuroscience Strategic Research Initiative) Grants Awarded recently:
Shannon L. Risacher, Ph.D. received a two-year grant for my project entitled “Visual biomarkers in preclinical and prodromal stages of Alzheimer’s disease.” The goal of this project is to evaluate measures of visual function and retinal morphology as biomarkers for AD in conjunction with known neuroimaging biomarkers of AD pathophysiology (i.e., advanced MRI and PET imaging) in a population of older adults at risk for cognitive decline.
Kwangsik Nho, Ph.D., was awarded a grant for a pilot project, where “we will perform whole genome sequencing on well-characterized participants from an extensively studied local cohort (Indiana Memory and Aging Study), which already has RNA-Seq and Proteomics data, and integrate cutting-edge ‘-omics’ data sets to better understand the molecular characteristics of Alzheimer’s disease (AD).”
Brenna McDonald, Ph.D. and Dr. Tom Talavage, Ph.D., of Purdue, are Co-PIs on a project titled “Multi-Site Evaluation of the Role of Deep Brain Structures in Long-Term Neurological Disorder after Traumatic Brain Injury”. The goal is to examine differences in MRI metrics of brain structure and function in children and adolescents who have experienced repetitive head impacts and/or concussion versus healthy controls who have not suffered traumatic brain injury, with an emphasis on white matter integrity and resting blood flow.
July 12 - 17, 2014 Drs. Andrew J. Saykin and Shannon L. Risacher presented at the Alzheimer's Association International Conference in Copenhagen, Denmark. You can find out what was presented here. The Center for Neuroimaging had a total of 13 presentations, with 2 of them being Oral.
July 2014 Published recently in the IN Scope weekly news for faculty, staff and students from the Indiana University School of Medicine: Exposure to TV violence related to irregular attention and brain structure . Congratulations to Drs. Tom Hummer and Yang Wang on their research findings.
June 2, 2014 IU School of Medicine Faculty members presented at American Society of Neuroradiology meeting in Montreal, May 17-22. Presentations were as follows:
Oral presentation: O-830 High Resolution Diffusion Tensor Imaging of the Optic Pathway in NF1 Patients with Readout-Segmented, Multi-Shot Echo Planar Imaging at 3 T C Ho1, J West1, C Lin1, S Kralik1, Y Wang1, D Porter2, A Saykin1, C Shih3
Oral Presentation: Odontogenic Infections—What Radiologists Should Know K Mosier
Oral presentation: O-456 Perfusion MR Imaging for Grading Pediatric Brain Tumors J Cardinal1, S Kralik2, A Kamer2, C Ho2
Oral presentation: O-197 Evaluation of a Novel Pulsed Arterial Spin Labeling Protocol in Pediatric Brain Tumors: A Feasibility Study in Comparison with Dynamic Susceptibility Contrast Perfusion C Ho1, S Kralik1, J Smith2, J Boaz2, L Ackerman2, D Fulkerson2, Y Wang1
Education Exhibit EE-78 Successful Use of the Amplatzer Vascular Plug II in the Setting of Acute Simultaneous Transection of the Cervical Internal Carotid and Vertebral Arteries D Murph1, D Hsu2, A DeNardo2
Electronic Education Exhibit eEdE-145 Rare and Aggressive Thyroid Carcinoma: You May Not Have Seen Them, But They May Have Seen You! J Sodergren1, S Kralik2, K Mosier2
Education Exhibit EE-65 Ectopic External Auditory Canal and Ossicular Formation in Goldenhar Syndrome N Supakul1, C Ho1
Electronic Education Exhibit eEdE-180 Fetal MR Imaging Technique: What Are We Looking for? N Supakul1, S Kralik1, C Ho1
Electronic Education Exhibit eEdE-55 The Faces of CNS Lymphoma M Broadbent1, P Mehta2, N Supakul2, I Wu2
Electronic Education Exhibit eEdE-187 Ultrafast MR Imaging Brain in Comparison with Head CT for the Diagnosis of Nonaccidental Trauma N Supakul1, S Kralik1, C Ho1O-862 Another Boring Case of NF2 – NOT!: Schwannomatosis N Koontz1, A Agarwal2, K Mosier2, L Shah3
Electronic Education Exhibit eEdE-02 Inferior Petrosal Sinus Sampling: What, Where, When, Why and How N Supakul1, J Tejada1This exhibit was awarded with an invitation for publication in the peer reviewed journal Neurographics.
May 30, 2014 Andrew J. Saykin, Psy.D., is invited to lecture at Washington University NIAC Seminar Series Lecture on 5/30/14. The title of his talk is “A Million Voxels and Three Billion Base Pairs: Challenges and Opportunities in the Imaging Genomics of Alzheimer’s Disease”
May 29, 2014 IU Simon Cancer Center hosts Cancer Research Day, with speakers Brenna McDonald, Psy.D.,MBA and Keynote Speaker Tim Ahles, Ph.D., who has collaborated with several faculty members in the Center for Neuroimaging. Read all about it here: http://cancer.iu.edu/education/crd/index.shtml
May 28th, 2014 Brenna McDonald, Psy.D.,MBA was recently in the News:
INVITED PODCAST: McDonald, B. C. (2014). Breast cancer chemotherapy effects on brain activation during multitasking and relation to cognitive complaints. Journal of Clinical Oncology. FEATURE STORY: http://www.reuters.com/article/2014/05/27/us-chemo-brain-mri-idUSKBN0E72IV20140527.
May 21-24 2014 Dr. Dan Albrecht and his supervisor Dr. Karmen Yoder are presenting The 10th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (Amsterdam, The Netherlands. NRM is a biennial international meeting attended by a range of experts in the neuroPET field. Topics range from novel tracer development, advances in tracer kinetic modeling, and application of PET neuroligands in both small animal models and human populations.
The posters they are presenting are: Albrecht DA, Christian BT, MacKie P, Yoder KK. (2014) Differences in dopamine function in fibromyalgia.
Yoder KK, Albrecht DS, Dzemidzic M, Herring CM, Walters JW, Hile KL, O’Connor SJ, Kareken DA. (2014) Intravenous alcohol-induced dopamine release occurs in different striatal subregions in nontreatment-seeking alcoholics and social drinkers.
Oberlin BG, Albrecht DS, Walters JW, Hile KL, Kareken DA, Yoder KK. (2014) Correlation of ventral striatal dopamine receptor availability and impulsive choice in alcoholics and social drinkers.
Yoder KK, Territo PR, Hutchins GD, Hannestad JO, Morris ED, Gallezot J-D, Normandin MD, Cosgrove KP. (2014) Comparison of Standardized Uptake Values with Volume of Distribution for Quantitation of [C11]PBR28 Brain Uptake.
Yoder KK, Liu N, Riley AA, McCarthy BP, Persohn S, West JD, Dzemidzic M, Territo P, Xu X (2014) Changes in brain blood flow and metabolism in a mouse model of traumatic brain injury are detectable with [64Cu]PTSM and [18F]FDG PET.
May 12 - 16, 2014 Six faculty from Imaging Sciences (Saykin, Lin, Wu, Wang, Dydak, Tirkes) as well as 2 graduate students (Ma, Yeh) presented their research findings last week at the Joint Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM) and the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) in Milan, Italy. Dr Saykin gave an invited talk on GWAS Studies of Imaging Phenotypes. The following two oral presentations and 11 posters were presented:
The 22th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Milan, Italy
1. Andy Saykin, GWAS Studies of Imaging Phenotypes (invited talk for Educational Course on MRomics)
2. Wu Y-C, Kodiweera C. Rotating Short-Axis EPI "blades" as veering diffusion gradient directions with composite reconstruction (RSA)
3. Ma R, Stock AK, Zauber SE, Murdoch JB, Dharmadhikari S, Long Z, Beste C, Dydak U. Manganese Induced Changes In Thalamic GABA Levels Influence Cognitive and Motor Performance.
1. Lin C, Liu K, Spottiswoode B, Buckwalter K. Feasibility of Hip Prosthesis Imaging at 3T.
2. Le Y, Kroeker R, Geppert C, Dale B, Kipfer HD, Lin C. A Simulation Study of the TWIST View Sharing Impact on the Breast DCE MRI.
3. Tirkes T, Lin C, Wang C, Mouser H, Kakarala B, Akisik F. Correlation of T1-weighted Gradient Echo (GRE) Signal Intensity and Decreased Exocrine Function in Suspected Early Chronic Pancreatitis.
4. Pooley RA, Gorny KR, Favazza CP, Felmlee JP, Lin C, Bernstein MA, Wharen RE. Temperature Measurements of Deep Brain Stimulator Lead Tip in Phantom With MR Body Coil RF Transmit.
5. Stirling BD, Wu Y-C, Sha L, Haxby J, Whalen PJ. Automated Segmentation of the Human Amygdala using High Angular Diffusion Imaging (HARDI) and Spectral k-means Clustering.
6. Kodiweera C, Alexander AL, Wu Y-C. Age and Gender - Related Changes in the Normal Human Brain Using Hybrid Diffusion Imaging (HYDI) with Neurite Orientation Dispersion and Density Imaging (NODDI) Analysis.
7. Dydak U, Ward EJ, Ma R, Snyder S, Zauber SE, Murdoch JB, Long Z, Rosenthal F. Occupational Manganese Exposure Levels Correlate with Brain GABA Levels.
8. Yeh CL, Zauber SE, Snyder S, Long Z, Dydak U. Motor and Cognitive Processing Networks show increased Manganese Accumulation in Metal Workers.
9. Dharmadhikari S, Yildiz A, Quetscher C, Chmielewski W, Dydak U, Beste C. Higher Striatal GABA Relates To A More Serial And Efficient Mode Of Action Cascading And Stronger Attentional Gating In Airplane Pilots.
10. Dharmadhikari S, Casjens S, Glaubitz B, Lehnert M, Quetscher C, Lotz A, Brüning T, Schmidt-Wilcke T, Beste C, Pesch B, Woitalla D, Dydak U. Correlation of GABA Levels and Motor Performance in Parkinson’s disease.
11. Long Z, Jiang YM, Li XR, Xu J, Yeh CL, Long LL, Zheng W, Murdoch JB, Dydak U. Increased Thalamic GABA and Decreased Glutamate-Glutamine in Chronic Manganese-exposed Metal Workers and Manganism Patients.
Dr. Andrew J. Saykin was invited to Lecture, GWAS Studies of Imaging Phenotypes, “MRomics” CCET Weekday Course, Organizers: James Gee, PhD, Kristine Glunde, PhD, & Elizabeth Morris, MD, 2014 Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM), Milan, Italy, May 14, 2014.
March 28, 2014
Drs. Brenna McDonald and Andrew Saykin, who spoke at the Indiana Health Law Review Symposium at the Indiana University Robert H. McKinney School of Law. The title of the symposium was Neuroscience and Law: Injury, Capacity, and Illness. Dr. McDonald served on the Child Contact Sports and Concussion panel (10:00-10:45 AM), while Dr. Saykin served on the Predictive Testing, Decision-Making, and Ethics panel (1:45-3:00 PM). For a complete symposium program, visit http://mckinneylaw.iu.edu/health-law/_brochures/IHLR-Symposium-2014.pdf
March 21, 2014
The Neuroscience Center will host the Indiana Alzheimer Disease Center (IADC) Scientific Symposium on Alzheimer's Disease: Early Detection and Intervention in the Goodman Hall Auditorium. Registration begins at 7:45 to hear speakers:
Andrew Saykin, PsyD, Raymond C. Beeler Professor of Radiology & Imaging Sciences and Director of the IADC, IUSM. Early Detection: The Role of Neuroimaging and Biomarkers
Eric Siemers, MD, Senior Medical Director of the Alzheimer’s Disease Team, Eli Lilly & Co. Development of Promising Early Treatments and Interventions
Benjamin G. Druss, M.D., M.P.H., Rosalynn Carter Chair in Mental Health, Department of Health Policy and Management, Rollins School of Public Health at Emory University. Improving Health and Healthcare for People with Serious Mental Illnesses: From Research to Practice and Back Again
Kelly Griese, Investor Education Coordinator, Indiana Secretary of State; and Brandy R. Matthews, MD, Assistant Professor of Clinical Neurology, Neurology Residency Program Director, Department of Neurology; Associate Leader, IADC Education Core, IUSM Preventing Elder Investment Fraud: Assessing for Vulnerability
Christopher M. Callahan, MD, FACP, Cornelius & Yvonne Pettinga Professor of Medicine, Department of Internal and Geriatric Medicine; Director, IU Center for Aging Research; Scientist, Regenstrief Institute, IUSM. Testing Interventions in the Home: The ADMIT Trial
Jill R. Murrell, PhD, Associate Professor, Department of Pathology & Laboratory Medicine and Medical and Molecular Genetics, IUSM. Genetics and Early Diagnosis
Frederick Unverzagt, PhD, Professor of Psychiatry, Director, Clinical Neuropsychology Residency, Department of Psychiatry; Associate Leader, IADC Clinical Core, IUSM. Update on Mental Engagement and Physical Exercise: Recipe for Successful Aging?